Holy Kujo

Holly Kujo (née Joestar (ホリィ・ジョースター)), known as Holley in the english version of the game, is a minor character appearing in Part III: Stardust Crusaders.

Personality
Holly's sweet charm is known by all. She believes in her son deeply, proud of the compassion that he has despite his hard shell. A woman who loves her family, she will deliberately lie about her illness so as to lessen their worry.

Stardust Crusaders
Holly's ailing condition becomes the catalyst for Jotaro and company's quest to Egypt. At the end of the adventure we see her back on her feet and once more the loving person she was.

JoJoLion
Holly is the mother of Yoshikage Kira in the alternate universe, making Kira of the alternate universe a direct descendent of Johnny Joestar. Holly Joestar Kira is revealed to have been an ophthalmologist who worked at the T.H. Medical University Hospital from 1998-2008 and is currently a guest professor at T.G. University. As of 2011 in the alternate universe, she is shown to be a patient at a hospital.

Stand
While Dio was alive, she developed a Stand but was incapable of using it both due to her gentle nature and not having the need to battle or fight.

Trivia

 * Her Japanese name is "Seiko" (聖子), meaning "holy girl". This is derived from a transliteration of her English name "Holly".
 * Holly's Stand is the only one in the series to inadvertently cause harm to its user. Her stand is also one of the only 'Unnamed Stands' in the entire series and it has no obvious abilities (besides causing harm to its user).
 * At the beginning of chapter 120, Holly is seen singing to herself. The lyrics are likely from the Kylie Minogue song "The Loco-Motion"