Board Thread:Manga Discussion/@comment-39718735-20200516000645/@comment-45522084-20200527114042

Pretty sure the requiem arrow is just an arrow that has a more potent virus, since to be able to get a stand from the arrow you need to be immune to the part of the virus that kills you since that's mostly how antagonists in part 4 got their stands and how the janitor died from getting stabbed with the arrow in part 5, it's basically just putting more of the virus into you, making your stand more potent or killing you because your immune system is too weak to withstand more of it. Unless wiki arrow page was wrong