Joestar Family

The Joestar Family (ジョースター家) is the main family featured in the JoJo's Bizarre Adventure series, of which each of the protagonists of the series is a part of. It is a powerful family with English roots; most of its members attract particular trials and tribulations when confronting their enemies. Each member of the bloodline has a star-shaped birthmark above their left shoulder blade – Dio Brando and his descendants have this distinguishable mark as well due to DIO's 'theft' of Jonathan Joestar's body, and thus inheriting the Joestar genes.

In the Steel Ball Run universe, Johnny Joestar marries Rina Higashikata, tying the Higashikata Family (and to a lesser extent, the Kujo Family) distantly to the Joestar family.

Trivia

 * Many members of the Joestar family, starting with Mary, had lived tragically short lives due to fatal encounters with supernatural foes.