Board Thread:Questions and Answers/@comment-39718735-20200611060928/@comment-45210418-20200611132320

This is a question I was going to ask, the anime says that the body is still alive in it's state. However, obliterating a vampire's brain kills it. DIO's head was split in two which does count as obliterating his brain, so DIO was already dead. We saw Esidisi die after his brain was obliterated, so the only possible way for him to come back was if in the short moment DIO stayed conscious, he preserved his brain somehow and possessed someone before daylight. This is assuming that Vampires can possess people through their brain like pillarmen, which is likely considering DIO steals Jonathan's body.