Board Thread:General Discussion/@comment-37836192-20181216174823/@comment-43434205-20190808150716

A viral stand could affect Giorno because viral infections are of ambivalent character in nature - they can be harmful or helpful. An infected cell may exhibit positive effects, but may lead to apoptosis later. Therefore, Giorno can be killed via a viral stand. If Giorno cannot be affected in this way, then any biochemical reaction in his body that would enfeeble him would be nullified. Getting tired, aging, eating would not affect Giorno at all, because these are all detrimental effects.

Let's brainstorm more: any brain-related, thought-altering Stand defeats GER easily, via this logical reasoning: Giorno's thoughts are altered by the Stand (here for example let's assume his thoughts are changed into never using GER again) => Giorno is rendered defenseless and is ultimately defeated.

Now, you may say that GER can reset the altering to zero, but that would imply its total autonomy, disproving total obediance to Giorno's ill-influenced will. Therefore, if GER has such a trait, it would make the Stand the master of the Stand User, deeming Giorno a slave of the Stand (a sleeping slave perhaps?).

It's not like we can deduce much, after all, GER is a vaguely-defined deus ex machima. What we have seen is the negation of Giorno's death (the timeskip was reversed because the result was Giorno's death, same with the blood dripping, or Mista shooting) so anything in between could not be prone to cancellation.