Board Thread:Anime/Game Discussion/@comment-38290213-20190619181504/@comment-39189388-20200906235350

Anything that deals physical damage (like Killer Queen) probably wouldn't work, since it can easily reform and regenerate after taking damage, and if Kira personally touched B.I.G it would just atach to him and split instead of being fully blown up.

The Hand and Cream both might have a chance, though its unknown whether they send things to some other dimension or if they kill things outright. Sending B.I.G to a pocket dimension could be a viable solution to get rid of it, but that wouldn't be 'killing' it.

Only thing I can think that could kill it is GER or The World Over Heaven since they can both rewrite reality, rendering B.I.G's physical abilities useless.

This being said, I think it would be really interesting if B.I.G got trapped in Superfly