Well TWOH’s ability (beyond time stop) is to rewrite reality in anyway DIO Over Heaven sees fit. Like how when Jotaro punched him in the skull like he did near the end of Stardust Crusaders and he was able to repair it on the spot where before, it left him crippled. So, it should stand to reason that TWOH can negate other op stand abilities like GER’s should DIO desired it.
But GER can nullify Dood will
But pales in comparison to a person who can rewrite what it can do.