I like how if somebody does something another person doesn't like on the internet, they're obviously a child

Randomly insulting a person on the internet is childish, so he is at the very least a manchild.

Ye i think killer queen can

You will be executed by Gyro Zeppeli for necroposting.

There are two stands I can think of that can either get rid of or erase the stand.

Cream - Vanilla Ice's Stand

The Hand - Okuyasu's Stand

Stop necroposting

This finished weeks ago.

I can perma kill BIG

There's a difference between "kill" and "incapacitate". I'm sure void-manipulating stands such as Cream and The Hand would be able to render it incapable of combat via transportation to their dimensions. GER could also reset BIG back to Carne, as other users have mentioned. However, none of this options would "kill" BIG. The only stand off the top of my head that could possibly kill BIG is Killer Queen, which would almost instantaneously disintegrate BIG. This doesn't account for the possibility that BIG could mitigate the damage by regenerating quickly enough (or by simply absorbing the energy). (I haven't read Jojo in a while, so my knowledge might be a bit rusty. Forgive me if I've made any mistakes.)

Edit: I just remembered that D4C would also have a decent chance at taking out BIG. It's victory conditions have similar caveats to Killer Queen. As long as it's able to obliterate BIG before it can heal, it should be able to win.

For what I know to kill it, it'll require for it to stop regenerating, so from what I've learned from my Greek Mythos, Fire could stop it from growing any bigger so Magician's Red, you can use acid against it so Yo Yo Ma would work, or you could erase it entirely with Killer Queen, Cream, or The Hand

The Green,Green Grass of Home can probably kill it, since it's just going to shrink until it gets squashed or doesn't exist