Guccio is a scrawny man with a triangular face, wide open eyes, a small flat nose, thin eyebrows, and a perpetually open mouth showing his teeth. Guccio sports a pencil mustache and a bowl cut, with two shoulder long strands of hair on each side of the head. He also dons pants that have the word Survivor on it referencing to his stand.
Guccio is a meek and cowardly man but somehow ended in the isolation ward. Fights used to naturally break out around him, even though he wasn't responsible.
Guccio's Stand, Survivor, given to him by Enrico Pucci, can influence people's minds through small electric signals, causing them to become extremely aggressive. Those influenced by the stand begin fighting indiscriminately while also powered up. Guccio will typically hide somewhere to avoid the mayhem.
While DIO had believed Pucci's Whitesnake to be superior for its stealing capabilities, he wondered if Pucci would betray him. The priest eventually confirms his loyalty, so DIO tells him the tale of a mountain lodger's Stand and how it drove men near him into a furious rage.
Coincidentally, Guccio also had the ability to cause people to fight since childhood. Fights would occur frequently around him, though he himself was never involved. After noticing Guccio's unfortunate ability, Pucci would later embed the mountain lodger's Stand into him in order to carry out his plans.
Guccio's prison card reveals that he received a 5 year-sentence at some point for sexual assault and theft.
Introduced as a cowardly figure in the high security ward, Guccio starts out begging for Anasui, Jolyne and F.F. to help him leave after all the other prisoners are drowned and turned to plants. The group doubts his alignment, so after planting Diver Down into Guccio, Anasui directs him towards the exit. Guccio is stopped by D an G briefly, but triggers the trap inside Guccio, causing ribs burst from his chest and impale D an G in the arm. After injuring him, Guccio wanders off dilapidated and presumably dies.
His corpse is later found by Pucci after the birth of the Green Baby. To celebrate, Pucci inserts a disc with the song Messiah by Georg Friedrich Händel into Guccio's head, causing him to play music much like a human stereo.